Membranoproliferative Glomerulonephritis

MPGN Types

Membranoproliferative Glomerulonephritis (MPGN) is a condition where deposits build up in the kidney's glomerular mesangium and basement membrane. This causes inflammation and thickening which damages the glomeruli (filters) of the kidney. As more glomeruli are damaged, the kidneys are unable to function properly.

MPGN may be caused by other diseases, such as systemic lupus erythematosis or chronic infections like Hepatitis C. However, in children most cases are idiopathic, and the cause is unknown.